Title : Gain of Function of Malate Dehydrogenase 2 and Familial Hyperglycemia.

Pub. Date : 2022 Feb 17

PMID : 34718610






2 Functional Relationships(s)
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Protein Name
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1 In transfected HepG2 cells, both variants significantly increased MDH2 enzymatic activity, thereby decreasing the NAD+/NADH ratio - a change known to affect insulin signaling and secretion. NAD insulin Homo sapiens
2 In transfected HepG2 cells, both variants significantly increased MDH2 enzymatic activity, thereby decreasing the NAD+/NADH ratio - a change known to affect insulin signaling and secretion. NAD insulin Homo sapiens