PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34718610-7 2022 In transfected HepG2 cells, both variants significantly increased MDH2 enzymatic activity, thereby decreasing the NAD+/NADH ratio - a change known to affect insulin signaling and secretion. NAD 114-118 insulin Homo sapiens 157-164 34718610-7 2022 In transfected HepG2 cells, both variants significantly increased MDH2 enzymatic activity, thereby decreasing the NAD+/NADH ratio - a change known to affect insulin signaling and secretion. NAD 119-123 insulin Homo sapiens 157-164