Pub. Date : 2021 Sep 30
PMID : 34680069
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | According to this perspective, the squalene synthase inhibitor Lapaquistat (TAK-475), originally developed as a cholesterol-lowering drug, might find a new indication in MKD, by modulating the mevalonate cholesterol pathway, increasing the availability of anti-inflammatory isoprenoid intermediates. | Cholesterol | farnesyl-diphosphate farnesyltransferase 1 | Homo sapiens |
| 2 | According to this perspective, the squalene synthase inhibitor Lapaquistat (TAK-475), originally developed as a cholesterol-lowering drug, might find a new indication in MKD, by modulating the mevalonate cholesterol pathway, increasing the availability of anti-inflammatory isoprenoid intermediates. | Cholesterol | farnesyl-diphosphate farnesyltransferase 1 | Homo sapiens |