PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34680069-5 2021 According to this perspective, the squalene synthase inhibitor Lapaquistat (TAK-475), originally developed as a cholesterol-lowering drug, might find a new indication in MKD, by modulating the mevalonate cholesterol pathway, increasing the availability of anti-inflammatory isoprenoid intermediates. Cholesterol 112-123 farnesyl-diphosphate farnesyltransferase 1 Homo sapiens 35-52 34680069-5 2021 According to this perspective, the squalene synthase inhibitor Lapaquistat (TAK-475), originally developed as a cholesterol-lowering drug, might find a new indication in MKD, by modulating the mevalonate cholesterol pathway, increasing the availability of anti-inflammatory isoprenoid intermediates. Cholesterol 204-215 farnesyl-diphosphate farnesyltransferase 1 Homo sapiens 35-52