Pub. Date : 2022 Feb 10
PMID : 34662393
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Covalent Bruton tyrosine kinase (BTK) inhibitors such as ibrutinib have proven to be highly beneficial in the treatment of chronic lymphocytic leukemia (CLL). | ibrutinib | Bruton agammaglobulinemia tyrosine kinase | Mus musculus |
| 2 | Covalent Bruton tyrosine kinase (BTK) inhibitors such as ibrutinib have proven to be highly beneficial in the treatment of chronic lymphocytic leukemia (CLL). | ibrutinib | Bruton agammaglobulinemia tyrosine kinase | Mus musculus |
| 3 | Thus, non-covalent BTK/ITK inhibitors such as vecabrutinib may be efficacious in C481S BTK mutant CLL, while preserving the T-cell immunomodulatory function of ibrutinib. | ibrutinib | Bruton agammaglobulinemia tyrosine kinase | Mus musculus |