Title : Difluoromethylornithine Induces Apoptosis through Regulation of AP-1 Signaling via JNK Phosphorylation in Epithelial Ovarian Cancer.

Pub. Date : 2021 Sep 23

PMID : 34638596






5 Functional Relationships(s)
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Compound Name
Protein Name
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1 Difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase (ODC), has promising activity against various cancers and a tolerable safety profile for long-term use as a chemopreventive agent. Eflornithine ornithine decarboxylase 1 Homo sapiens
2 Difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase (ODC), has promising activity against various cancers and a tolerable safety profile for long-term use as a chemopreventive agent. Eflornithine ornithine decarboxylase 1 Homo sapiens
3 Difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase (ODC), has promising activity against various cancers and a tolerable safety profile for long-term use as a chemopreventive agent. Eflornithine ornithine decarboxylase 1 Homo sapiens
4 Difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase (ODC), has promising activity against various cancers and a tolerable safety profile for long-term use as a chemopreventive agent. Eflornithine ornithine decarboxylase 1 Homo sapiens
5 DFMO treatment inhibited the activity and downregulated the expression of ODC in ovarian cancer cells. Eflornithine ornithine decarboxylase 1 Homo sapiens