| Protein Name | ornithine decarboxylase 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 4953 |
| Gene Symbol | ODC1 |
| UniProt | P11926 (DCOR_HUMAN), B4DXF8 (B4DXF8_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
714
Total Number of Articles : 1405 |
Description |
ornithine decarboxylase 1 |
| Gene Summary |
This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013] |
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