Protein Name ornithine decarboxylase 1
Organism Homo sapiens
Gene ID 4953
Gene Symbol


UniProt P11926 (DCOR_HUMAN), B4DXF8 (B4DXF8_HUMAN)
Relationships Total Number of functionally related compound(s) : 714
Total Number of Articles : 1405

ornithine decarboxylase 1

Gene Summary

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013]

  • ornithine decarboxylase
  • BABS
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