Title : Treatment of Metastatic Castration-resistant Prostate Cancer: Are PARP Inhibitors Shifting the Paradigm?

Pub. Date : 2021 Oct

PMID : 34593416






2 Functional Relationships(s)
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1 However, not only PARP inhibitors, but also chemotherapeutic agents such as platinum agents, taxanes, and radium-223 are active in HRR gene mutation carriers, and platinum sensitivity may predict the efficacy of PARP inhibitors for mCRPC. Platinum poly(ADP-ribose) polymerase 1 Homo sapiens
2 However, not only PARP inhibitors, but also chemotherapeutic agents such as platinum agents, taxanes, and radium-223 are active in HRR gene mutation carriers, and platinum sensitivity may predict the efficacy of PARP inhibitors for mCRPC. Platinum poly(ADP-ribose) polymerase 1 Homo sapiens