Pub. Date : 2021 Aug 25
PMID : 34572484
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Growth Suppression in Lung Cancer Cells Harboring EGFR-C797S Mutation by Quercetin. | Quercetin | epidermal growth factor receptor | Homo sapiens |
| 2 | As quercetin was recently shown to inhibit AXL, quercetin may be effective in treating NSCLC cells harboring the EGFR C797S mutation. | Quercetin | epidermal growth factor receptor | Homo sapiens |
| 3 | In this work, the cytotoxic effects of quercetin and its ability to inhibit tumor growth were examined in TKI-resistant NSCLC cells harboring the EGFR C797S mutation. | Quercetin | epidermal growth factor receptor | Homo sapiens |
| 4 | We demonstrated that quercetin exhibited potent cytotoxic effects on NSCLC cells harboring the EGFR C797S mutation by inhibiting AXL and inducing apoptosis. | Quercetin | epidermal growth factor receptor | Homo sapiens |
| 5 | Quercetin inhibited the tumor growth of xenografted NSCLC cells harboring the EGFR C797S mutation and appeared to act synergistically with brigatinib to inhibit of tumor growth in vivo. | Quercetin | epidermal growth factor receptor | Homo sapiens |
| 6 | In summary, herein, we revealed that quercetin is an effective inhibitor for the treatment of non-small-cell lung cancer harboring the EGFR C797S mutation. | Quercetin | epidermal growth factor receptor | Homo sapiens |