PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34572484-0 2021 Growth Suppression in Lung Cancer Cells Harboring EGFR-C797S Mutation by Quercetin. Quercetin 73-82 epidermal growth factor receptor Homo sapiens 50-54 34572484-5 2021 As quercetin was recently shown to inhibit AXL, quercetin may be effective in treating NSCLC cells harboring the EGFR C797S mutation. Quercetin 48-57 epidermal growth factor receptor Homo sapiens 113-117 34572484-6 2021 In this work, the cytotoxic effects of quercetin and its ability to inhibit tumor growth were examined in TKI-resistant NSCLC cells harboring the EGFR C797S mutation. Quercetin 39-48 epidermal growth factor receptor Homo sapiens 146-150 34572484-7 2021 We demonstrated that quercetin exhibited potent cytotoxic effects on NSCLC cells harboring the EGFR C797S mutation by inhibiting AXL and inducing apoptosis. Quercetin 21-30 epidermal growth factor receptor Homo sapiens 95-99 34572484-8 2021 Quercetin inhibited the tumor growth of xenografted NSCLC cells harboring the EGFR C797S mutation and appeared to act synergistically with brigatinib to inhibit of tumor growth in vivo. Quercetin 0-9 epidermal growth factor receptor Homo sapiens 78-82 34572484-9 2021 In summary, herein, we revealed that quercetin is an effective inhibitor for the treatment of non-small-cell lung cancer harboring the EGFR C797S mutation. Quercetin 37-46 epidermal growth factor receptor Homo sapiens 135-139