PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34320371-5 2021 Based on the findings of thirteen tumor entities, we identified three resistance groups, where group 1 (endodermal origin) prominently indicates NRF2-pathway activation, group 2 (mesodermal origin, primordial germ cells) shares elevated DNA repair mechanisms and decreased apoptosis induction, and group 3 (ectodermal and paraxial mesodermal origin) commonly presents deregulated apoptosis induction and alternating pathways as the main cisplatin-induced resistance mechanisms. Cisplatin 437-446 NFE2 like bZIP transcription factor 2 Homo sapiens 145-149