Pub. Date : 2021 Jun
PMID : 34277796
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | GO semantic similarity analysis showed that notoginsenoside R1 might play a role in regulating interleukin 17 (IL-17) signal pathway, tumor necrosis factor (TNF) signal pathway and other key links by regulating MAPK1, MAPK3, IL-1beta and other targets. | notoginsenoside R1 | interleukin 1 alpha | Rattus norvegicus |
| 2 | The results of pharmacological experiments showed that notoginsenoside R1 could significantly reduce the wet:dry ratio of the lung in an animal model of ALI, improve the pathological injury of the lung, and reduce the content of IL-1beta in serum and in bronchoalveolar lavage fluid (BALF) of experimental animals. | notoginsenoside R1 | interleukin 1 alpha | Rattus norvegicus |