Title : Hepatoprotective effects of phytochemicals berberine and umbelliferone against methotrexate-induced hepatic intoxication: experimental studies and in silico evidence.

Pub. Date : 2021 Dec

PMID : 34258700






1 Functional Relationships(s)
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1 More importantly, BBR resulted in reducing P38 mitogen-activated protein kinase (P38MAPK), nuclear factor kappa-B (NF-kappaB), and Kelch-like ECH-associated protein 1 (Keap-1) genes and enhanced mRNA expression of Nrf-2 (P < 0.05). Berberine NFE2 like bZIP transcription factor 2 Homo sapiens