Title : Association of T2285C polymorphism in PARP1 gene coding region with its expression, activity and NSCLC risk along with prognosis.

Pub. Date : 2021 Aug 27

PMID : 34132814






1 Functional Relationships(s)
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1 These findings suggest the variant allele C of T2285C polymorphism of PARP1 linked to an increase of NSCLC risk, and unfavorable efficacy and prognosis of NSCLC patients with platinum-based chemotherapy, which might be associated with enhancement of its mRNA expression and the diminishment of activity. Platinum poly(ADP-ribose) polymerase 1 Homo sapiens