Title : Molecular Mechanisms of Chemotherapy Resistance in Head and Neck Cancers.

Pub. Date : 2021

PMID : 34026617






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1 In this review, we first summarize the molecular mechanisms of chemotherapy resistance that occur during the treatment with cisplatin, 5-fluorouracil, and docetaxel/paclitaxel, including DNA/RNA damage repair, drug efflux, apoptosis inhibition, and epidermal growth factor receptor/focal adhesion kinase/nuclear factor-kappaB activation. Cisplatin epidermal growth factor receptor Homo sapiens