Title : TGFBI is involved in the formation of polyploid cancer cells and the response to paclitaxel.

Pub. Date : 2021 Apr

PMID : 33987391






3 Functional Relationships(s)
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1 TGFBI is involved in the formation of polyploid cancer cells and the response to paclitaxel. Paclitaxel transforming growth factor beta induced Homo sapiens
2 Compared with the empty vector, under paclitaxel treatment, the over-expression of TGFBI in MDA-MB-231 and T-MDA-MB-231 both showed a higher growth inhibition rate. Paclitaxel transforming growth factor beta induced Homo sapiens
3 Conclusions: TGFBI can increase the sensitivity of paclitaxel in polyploid cancer cells and participate in the formation of polyploidy in MDA-MB-231 induced by nocodazole. Paclitaxel transforming growth factor beta induced Homo sapiens