Protein Name transforming growth factor beta induced
Organism Homo sapiens
Gene ID 7045
Gene Symbol


UniProt Q15582 (BGH3_HUMAN), A0A0S2Z4Q2 (A0A0S2Z4Q2_HUMAN)
Relationships Total Number of functionally related compound(s) : 193
Total Number of Articles : 193

transforming growth factor beta induced

Gene Summary

This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]

  • transforming growth factor-beta-induced protein ig-h3
  • RGD-containing collagen-associated protein
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