Title : Inositol treatment inhibits medulloblastoma through suppression of epigenetic-driven metabolic adaptation.

Pub. Date : 2021 Apr 12

PMID : 33846320






1 Functional Relationships(s)
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1 We demonstrate mTOR pathway activation and metabolic adaptation specifically in medulloblastoma of the molecular subgroup G4 characterised by a BMI1High;CHD7Low signature and show this can be counteracted by IP6 treatment. Phytic Acid mechanistic target of rapamycin kinase Homo sapiens