Title : Proteomic analysis identified LBP and CD14 as key proteins in blood/biphasic calcium phosphate microparticle interactions.

Pub. Date : 2021 Jun

PMID : 33831568






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here, using proteomic analyses we showed that the osteogenic properties of 80-200 microm BCP particles embedded in a blood clot is associated with a higher expression of fibrinogen. hydroxyapatite-beta tricalcium phosphate fibrinogen beta chain Homo sapiens
2 Fibrinogen upregulates the Myd88- and NF-kappaB-dependent TLR4 pathway in blood cells and, BCP-induced TLR4 activation is mediated by the LBP and CD14 proteins. hydroxyapatite-beta tricalcium phosphate fibrinogen beta chain Homo sapiens