Pub. Date : 2021 Apr 7
PMID : 33828191
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we developed a bispecific antibody (BsAb; mPEG x HER2) that can easily provide HER2+ tumor tropism to mPEGylated liposomal doxorubicin (PLD) and further increase the drug accumulation in cancer cells via receptor-mediated endocytosis, and improve the cytotoxicity and therapeutic efficacy of HER2+ ovarian tumors. | Doxorubicin | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |
| 2 | Here, we developed a bispecific antibody (BsAb; mPEG x HER2) that can easily provide HER2+ tumor tropism to mPEGylated liposomal doxorubicin (PLD) and further increase the drug accumulation in cancer cells via receptor-mediated endocytosis, and improve the cytotoxicity and therapeutic efficacy of HER2+ ovarian tumors. | Doxorubicin | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |