Title : Dual Inhibition of Ornithine Decarboxylase and A1 Adenosine Receptor Efficiently Suppresses Breast Tumor Cells.

Pub. Date : 2021

PMID : 33777791






4 Functional Relationships(s)
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1 Next, we investigated a dual inhibitor (ODC-MPI-2) of A1AR and ODC (ornithine decarboxylase 1), the rate-limiting enzyme in polyamine biosynthesis. Polyamines ornithine decarboxylase 1 Homo sapiens
2 Next, we investigated a dual inhibitor (ODC-MPI-2) of A1AR and ODC (ornithine decarboxylase 1), the rate-limiting enzyme in polyamine biosynthesis. Polyamines ornithine decarboxylase 1 Homo sapiens
3 Next, we investigated a dual inhibitor (ODC-MPI-2) of A1AR and ODC (ornithine decarboxylase 1), the rate-limiting enzyme in polyamine biosynthesis. Polyamines ornithine decarboxylase 1 Homo sapiens
4 We also demonstrated that ODC-MPI-2 reduces cellular polyamine levels and elevates cAMP concentration. Polyamines ornithine decarboxylase 1 Homo sapiens