Title : Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting.

Pub. Date : 2021 Mar 25

PMID : 33710891






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Folic Acid-Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting. Folic Acid thymidylate synthetase Homo sapiens
2 Accordingly, we have designed conjugates of folic acid with anticancer peptides able to bind human thymidylate synthase (hTS) and enter cancer cells through folate receptor alpha (FRalpha) highly expressed by several cancer cells. Folic Acid thymidylate synthetase Homo sapiens