Title : Prostaglandin E2 promotes pathological retinal neovascularisation via EP4R-EGFR-Gab1-AKT signaling pathway.

Pub. Date : 2021 Apr

PMID : 33609510






2 Functional Relationships(s)
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1 In addition, AH23848 treatment attenuated PGE2-or cay10598-induced proliferation and migration by repressing the EGF receptor (EGFR)/Growth factor receptor bound protein 2-associated binder protein 1 (Gab1)/Akt/NF-kappaB/VEGF-A signaling network in human retinal microvascular endothelial cells (hRMECs). Dinoprostone epidermal growth factor receptor Homo sapiens
2 In addition, AH23848 treatment attenuated PGE2-or cay10598-induced proliferation and migration by repressing the EGF receptor (EGFR)/Growth factor receptor bound protein 2-associated binder protein 1 (Gab1)/Akt/NF-kappaB/VEGF-A signaling network in human retinal microvascular endothelial cells (hRMECs). Dinoprostone epidermal growth factor receptor Homo sapiens