Title : NQO1 mediates the anti-inflammatory effects of nootkatone in lipopolysaccharide-induced neuroinflammation by modulating the AMPK signaling pathway.

Pub. Date : 2021 Feb 20

PMID : 33460769






1 Functional Relationships(s)
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1 Treatment of BV2 cells with the NQO1-specific inhibitor, dicoumarol, or with NQO1 siRNA significantly blocked NKT-mediated inhibition of NO, ROS, TNF-alpha, IL-1beta, and upregulation of IL-10. Dicumarol tumor necrosis factor Mus musculus