Pub. Date : 2021 Jan 15
PMID : 33249060
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here, we describe the anti-COVID-19 potential of PTC299, an orally bioavailable compound that is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), the rate-limiting enzyme of the de novo pyrimidine nucleotide biosynthesis pathway. | Pyrimidine Nucleotides | dihydroorotate dehydrogenase (quinone) | Homo sapiens |