Pub. Date : 2020
PMID : 33177988
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study investigated the clearance effects of hepcidin on alpha-syn induced by a relatively low concentration of rotenone exposure or alpha-syn overexpression to elucidate the potential clearance pathway involved in this process. | Rotenone | synuclein alpha | Homo sapiens |
| 2 | alpha-syn expression and iron content increased under a low concentration rotenone (25 nM for 3 days) treatment in SH-SY5Y cells. | Rotenone | synuclein alpha | Homo sapiens |
| 3 | Hepcidin also played a role in reducing alpha-syn accumulation in rotenone and alpha-syn overexpression conditions. | Rotenone | synuclein alpha | Homo sapiens |
| 4 | In conclusion, hepcidin eliminated alpha-syn expression via the autophagy pathway in rotenone-treated and alpha-syn overexpression SH-SY5Y cells. | Rotenone | synuclein alpha | Homo sapiens |