Title : An Adaptive Control Scheme for Interleukin-2 Therapy.

Pub. Date : 2020 Nov 20

PMID : 33134893






2 Functional Relationships(s)
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1 By using a mechanistic mathematical model, we introduced an adaptive control strategy to design the minimal therapeutic IL-2 dosage required to increase and stabilize Treg population and restrict inflammatory response. treg interleukin 2 Homo sapiens
2 Our simulation results showed that a minimal Treg population was required to restrict the transient side effect of IL-2 injections on the effector Tconv response. treg interleukin 2 Homo sapiens