PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33134893-4 2020 By using a mechanistic mathematical model, we introduced an adaptive control strategy to design the minimal therapeutic IL-2 dosage required to increase and stabilize Treg population and restrict inflammatory response. treg 167-171 interleukin 2 Homo sapiens 120-124 33134893-6 2020 Our simulation results showed that a minimal Treg population was required to restrict the transient side effect of IL-2 injections on the effector Tconv response. treg 45-49 interleukin 2 Homo sapiens 115-119