Title : The tea catechin epigallocatechin gallate inhibits NF-κB-mediated transcriptional activation by covalent modification.

Pub. Date : 2020 Nov 30

PMID : 33038311






1 Functional Relationships(s)
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1 We analyzed and discovered a novel mechanism by which epigallocatechin gallate (EGCG), the most abundant polyphenol in tea and a putative health-promoting constituent, inhibits activation of the nuclear transcription factor NF-kappaB, which mediates inflammatory responses to cytokines and other agents. Polyphenols nuclear factor kappa B subunit 1 Homo sapiens