Pub. Date : 2020
PMID : 32982390
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hence, we conducted in vitro studies, to elucidate the efficacy and mechanisms of CBD for inhibiting neuronal hypersensitivity in cultured rat sensory neurons, following activation of TRPV1. | Cannabidiol | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 2 | Conclusion: CBD at low doses corresponding to plasma concentrations observed physiologically inhibits or desensitizes neuronal TRPV1 signalling by inhibiting the adenylyl cyclase - cAMP pathway, which is essential for maintaining TRPV1 phosphorylation and sensitization. | Cannabidiol | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |
| 3 | Conclusion: CBD at low doses corresponding to plasma concentrations observed physiologically inhibits or desensitizes neuronal TRPV1 signalling by inhibiting the adenylyl cyclase - cAMP pathway, which is essential for maintaining TRPV1 phosphorylation and sensitization. | Cannabidiol | transient receptor potential cation channel, subfamily V, member 1 | Rattus norvegicus |