Protein Name | transient receptor potential cation channel, subfamily V, member 1 |
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Organism | Rattus norvegicus |
Gene ID | 83810 |
Gene Symbol | Trpv1 |
UniProt | O35433 (TRPV1_RAT) |
Relationships |
Total Number of functionally related compound(s) :
716
Total Number of Articles : 1325 |
Description |
transient receptor potential cation channel, subfamily V, member 1 |
Gene Summary |
Enables several functions, including ATP binding activity; calmodulin binding activity; and ligand-gated monoatomic ion channel activity. Involved in several processes, including calcium ion import across plasma membrane; cellular response to temperature stimulus; and regulation of blood circulation. Acts upstream of or within response to heat and response to pH. Located in several cellular components, including external side of plasma membrane; neuronal cell body; and sarcoplasmic reticulum. Is active in postsynaptic membrane. Used to study myocardial infarction and reflex epilepsy. Human ortholog(s) of this gene implicated in migraine. Orthologous to human TRPV1 (transient receptor potential cation channel subfamily V member 1). [provided by Alliance of Genome Resources, Jul 2025] |
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Properties | |