Title : Effect of nicotine on placental inflammation and apoptosis in preeclampsia-like model.

Pub. Date : 2020 Nov 15

PMID : 32835699






1 Functional Relationships(s)
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1 A significant upregulation in mRNA expression of TNF-alpha, IL-1beta, MCP-1, and caspase 3, caspase 8, caspase 9 was found in the PE-like rats compared to the control animals, the immunoreactivity of placental MCP-1, TNFR1, and apoptosis-related proteins (caspase 3, caspase 8, caspase 9, Bax) was also enhanced; nicotine treatment significantly reversed those changes. Nicotine tumor necrosis factor Rattus norvegicus