Title : Hypoxic preconditioning combined with curcumin promotes cell survival and mitochondrial quality of bone marrow mesenchymal stem cells, and accelerates cutaneous wound healing via PGC-1α/SIRT3/HIF-1α signaling.

Pub. Date : 2020 Nov 1

PMID : 32745765






1 Functional Relationships(s)
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1 Notably, SIRT3 RNAi suppressed OXPHOS activity, while PGC-1alpha RNAi triggered mitochondrial superoxide and intracellular H2O2 production in hypoxia combined with curcumin-treated BMSCs. Superoxides peroxisome proliferative activated receptor, gamma, coactivator 1 alpha Mus musculus