Title : Targeting the NO-cGMP-PDE5 pathway in COVID-19 infection. The DEDALO project.

Pub. Date : 2021 Jan

PMID : 32526061






2 Functional Relationships(s)
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1 Targeting the NO-cGMP-PDE5 pathway in COVID-19 infection. Cyclic GMP phosphodiesterase 5A Homo sapiens
2 MATERIALS AND METHODS: We performed a systematic review of all evidence documenting any involvement of the NO-cGMP-PDE5 axis in the pathophysiology of COVID-19, presenting the ongoing clinical trials aimed at modulating this axis, including our own "silDEnafil administration in DiAbetic and dysmetaboLic patients with COVID-19 (DEDALO trial)." Cyclic GMP phosphodiesterase 5A Homo sapiens