Title : The prolyl hydroxylase inhibitor roxadustat: Paradigm in drug discovery and prospects for clinical application beyond anemia.

Pub. Date : 2020 Jul

PMID : 32380083






1 Functional Relationships(s)
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1 Prolyl hydroxylase (PHD) inhibitors, such as roxadustat, can stabilize hypoxia-inducible factor (HIF)-2alpha and induce erythropoietin (EPO) production under normal conditions. roxadustat endothelial PAS domain protein 1 Homo sapiens