Title : Anticancer evaluation of a manganese complex on HeLa and MCF-7 cancer cells: design, deterministic solvothermal synthesis approach, Hirshfeld analysis, DNA binding, intracellular reactive oxygen species production, electrochemical characterization and density functional theory.

Pub. Date : 2021 Feb

PMID : 32041485






3 Functional Relationships(s)
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1 Furthermore, an assessment of caspase-9 and caspase-3 activity after exposure to compound Mn(phen)2Cl2 in HeLa cells indicated that at IC50 values of Mn(phen)2Cl2, 1.5 folds and 4.8 folds" increase in caspase-9 and caspase-3 activity, respectively, occurs. manganese chloride caspase 9 Homo sapiens
2 Furthermore, an assessment of caspase-9 and caspase-3 activity after exposure to compound Mn(phen)2Cl2 in HeLa cells indicated that at IC50 values of Mn(phen)2Cl2, 1.5 folds and 4.8 folds" increase in caspase-9 and caspase-3 activity, respectively, occurs. manganese chloride caspase 9 Homo sapiens
3 Furthermore, an assessment of caspase-9 and caspase-3 activity after exposure to compound Mn(phen)2Cl2 in HeLa cells indicated that at IC50 values of Mn(phen)2Cl2, 1.5 folds and 4.8 folds" increase in caspase-9 and caspase-3 activity, respectively, occurs. manganese chloride caspase 9 Homo sapiens