Title : Multiple myeloma with 1q21 amplification is highly sensitive to MCL-1 targeting.

Pub. Date : 2019 Dec 23

PMID : 31856269






1 Functional Relationships(s)
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1 In this study, we investigated whether sensitivity to the novel MCL-1 inhibitor S63845 could be predicted using cytogenetics, focusing on amplification of 1q21, the chromosomal region that contains the MCL1 locus. S63845 MCL1 apoptosis regulator, BCL2 family member Homo sapiens