Pub. Date : 2020 Feb
PMID : 31831259
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Further study indicated that GdCl3 could induce the binding of CaSR and TbetaR II and then both of these two receptors translocated from cell membrane to cytoplasm, in this case, TbetaR II on the cell membrane was decreased and then desensitized to the stimulation of its ligand TGF-beta1, so that the activation of its downstream factors such as Smad2 and Smad3 were blocked, finally, ECM expression in mesangial cells were inhibited. | Gadolinium | SMAD family member 2 | Rattus norvegicus |