Title : Early identification of promiscuous attributes of aldose reductase inhibitors using a DMSO-perturbation assay.

Pub. Date : 2020 Jan 15

PMID : 31744675






2 Functional Relationships(s)
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1 The present study examined the AR inhibitory effects of novel synthetic hydantoins and their structural relatives, some of which were obtained from chemically engineered extracts of natural plants, and discovered several novel AR inhibitors with moderate inhibitory activity. Hydantoins aldo-keto reductase family 1 member B Homo sapiens
2 The present study examined the AR inhibitory effects of novel synthetic hydantoins and their structural relatives, some of which were obtained from chemically engineered extracts of natural plants, and discovered several novel AR inhibitors with moderate inhibitory activity. Hydantoins aldo-keto reductase family 1 member B Homo sapiens