Pub. Date : 2020 Jan
PMID : 31646664
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The dose-dependent protective effects against H2 O2 -induced oxidative stress of the rutin-Lys MRPs may involve the inhibition of reactive oxygen species generation, enhancement of the superoxide dismutase and catalase activities, along with the activation of the Nrf2-dependent pathway and upregulation of phase II antioxidant genes (including NQO1, HO-1, GCLG, and GCLM). | Rutin | NFE2 like bZIP transcription factor 2 | Homo sapiens |
2 | This study shows that a 30-min thermal treatment at 120 C generates antioxidative MRPs in the rutin-Lys, rutin-His, rutin-Ile and rutin-Glu model systems, which can directly inhibit reactive oxygen species generation and enhance SOD and CAT activities while activating the Nrf2-dependent pathway and upregulating the expression of phase II detoxifying antioxidant genes. | Rutin | NFE2 like bZIP transcription factor 2 | Homo sapiens |
3 | This study shows that a 30-min thermal treatment at 120 C generates antioxidative MRPs in the rutin-Lys, rutin-His, rutin-Ile and rutin-Glu model systems, which can directly inhibit reactive oxygen species generation and enhance SOD and CAT activities while activating the Nrf2-dependent pathway and upregulating the expression of phase II detoxifying antioxidant genes. | Rutin | NFE2 like bZIP transcription factor 2 | Homo sapiens |