Title : A novel FTY720 analogue targets SET-PP2A interaction and inhibits growth of acute myeloid leukemia cells without inducing cardiac toxicity.

Pub. Date : 2020 Jan 1

PMID : 31593801






2 Functional Relationships(s)
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1 The PP2A activating drug FTY720 has potent anti-leukemic effects; nevertheless, FTY720 induces cardiotoxicity at the anti-neoplastic dose. Fingolimod Hydrochloride protein phosphatase 2 phosphatase activator Homo sapiens
2 The PP2A activating drug FTY720 has potent anti-leukemic effects; nevertheless, FTY720 induces cardiotoxicity at the anti-neoplastic dose. Fingolimod Hydrochloride protein phosphatase 2 phosphatase activator Homo sapiens