Protein Name protein phosphatase 2 phosphatase activator
Organism Homo sapiens
Gene ID 5524
Gene Symbol


Relationships Total Number of functionally related compound(s) : 675
Total Number of Articles : 1345

protein phosphatase 2 phosphatase activator

Gene Summary

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

  • serine/threonine-protein phosphatase 2A activator
  • PP2A phosphatase activator
  • phosphotyrosyl phosphatase activator
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