Title : Epidermal growth factor receptor/heme oxygenase-1 axis is involved in chemoresistance to cisplatin and pirarubicin in HepG2 cell lines and hepatoblastoma specimens.

Pub. Date : 2019 Dec

PMID : 31559456






3 Functional Relationships(s)
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Protein Name
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1 Epidermal growth factor receptor/heme oxygenase-1 axis is involved in chemoresistance to cisplatin and pirarubicin in HepG2 cell lines and hepatoblastoma specimens. Cisplatin epidermal growth factor receptor Homo sapiens
2 Combination treatment of EGFR inhibitor with CDDP and THP increased the cytotoxic effect in HepG2 cells. Cisplatin epidermal growth factor receptor Homo sapiens
3 CONCLUSION: The cytotoxic effects of CDDP and THP were both enhanced under HO-1 knockdown conditions as well as under conditions that inhibit the activation pathway of HO-1 by EGFR inhibitors. Cisplatin epidermal growth factor receptor Homo sapiens