Title : Microwave-Assisted Organic Synthesis, structure-activity relationship, kinetics and molecular docking studies of non-cytotoxic benzamide derivatives as selective butyrylcholinesterase inhibitors.

Pub. Date : 2019 Sep 15

PMID : 31378596






1 Functional Relationships(s)
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1 Among them, compound 3 revealed the most potent BCHE inhibitory activity (IC50 = 0.8 +- 0.6 microM) when compared with the standard galantamine hydrobromide (IC50 = 40.83 +- 0.37 microM). Galantamine butyrylcholinesterase Homo sapiens