Protein Name butyrylcholinesterase
Organism Homo sapiens
Gene ID 590
Gene Symbol


UniProt P06276 (CHLE_HUMAN)
Relationships Total Number of functionally related compound(s) : 2300
Total Number of Articles : 4094


Gene Summary

This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine. [provided by RefSeq, Jul 2016]

  • cholinesterase
  • acylcholine acylhydrolase
  • butyrylcholine esterase
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