Pub. Date : 2019 Sep 1
PMID : 30986422
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Alpha-lipoic acid alleviated 6-OHDA-induced cell damage by inhibiting AMPK/mTOR mediated autophagy. | Thioctic Acid | mechanistic target of rapamycin kinase | Homo sapiens |
2 | Furthermore, we found that ALA inhibited AMPK phosphorylation while activated mTOR phosphorylation thereby blocking AMPK/mTOR signaling pathway involved autophagy. | Thioctic Acid | mechanistic target of rapamycin kinase | Homo sapiens |
3 | Furthermore, we found that ALA inhibited AMPK phosphorylation while activated mTOR phosphorylation thereby blocking AMPK/mTOR signaling pathway involved autophagy. | Thioctic Acid | mechanistic target of rapamycin kinase | Homo sapiens |
4 | In conclusion, ALA alleviated 6-OHDA induced cell injury possibly by inhibiting autophagy mediated by AMPK/mTOR pathway. | Thioctic Acid | mechanistic target of rapamycin kinase | Homo sapiens |