Title : Alpha-lipoic acid alleviated 6-OHDA-induced cell damage by inhibiting AMPK/mTOR mediated autophagy.

Pub. Date : 2019 Sep 1

PMID : 30986422






4 Functional Relationships(s)
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1 Alpha-lipoic acid alleviated 6-OHDA-induced cell damage by inhibiting AMPK/mTOR mediated autophagy. Thioctic Acid mechanistic target of rapamycin kinase Homo sapiens
2 Furthermore, we found that ALA inhibited AMPK phosphorylation while activated mTOR phosphorylation thereby blocking AMPK/mTOR signaling pathway involved autophagy. Thioctic Acid mechanistic target of rapamycin kinase Homo sapiens
3 Furthermore, we found that ALA inhibited AMPK phosphorylation while activated mTOR phosphorylation thereby blocking AMPK/mTOR signaling pathway involved autophagy. Thioctic Acid mechanistic target of rapamycin kinase Homo sapiens
4 In conclusion, ALA alleviated 6-OHDA induced cell injury possibly by inhibiting autophagy mediated by AMPK/mTOR pathway. Thioctic Acid mechanistic target of rapamycin kinase Homo sapiens