Title : The NMR-based characterization of the FTY720-SET complex reveals an alternative mechanism for the attenuation of the inhibitory SET-PP2A interaction.

Pub. Date : 2019 Jun

PMID : 30917007






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Targeting SET with a sphingolipid analog drug fingolimod (FTY720) or ceramide leads to the reactivation of tumor suppressor PP2A. Ceramides protein phosphatase 2 phosphatase activator Homo sapiens