Title : Cell Cycle Arrest and Cytotoxic Effects of SAHA and RG7388 Mediated through p21WAF1/CIP1 and p27KIP1 in Cancer Cells.

Pub. Date : 2019 Jan 29

PMID : 30700046






1 Functional Relationships(s)
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1 The small molecule RG7388 (idasanutlin, R05503781) is a newly developed inhibitor that is specific for an oncogene-derived protein called MDM2, which is also in clinical trials for the treatment of various types of cancers. RG7388 MDM2 proto-oncogene Homo sapiens