Pub. Date : 2018 Dec 14
PMID : 30647852
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Chronic lymphocytic leukemia cells from ibrutinib treated patients are sensitive to Axl receptor tyrosine kinase inhibitor therapy. | ibrutinib | AXL receptor tyrosine kinase | Homo sapiens |
2 | Ibrutinib-exposed CLL B-cells were treated with increasing doses (0.01- 0.50muM) of a new formulation of high-affinity Axl inhibitor, TP-0903 (tartrate salt), for 24 hours and LD50 doses were determined. | ibrutinib | AXL receptor tyrosine kinase | Homo sapiens |
3 | We detected sustained overexpression of Axl in CLL B-cells from CLL patients on ibrutinib treatment, suggests targeting Axl could be a promising strategy to overcome drug resistance and killing of CLL B-cells in these patients. | ibrutinib | AXL receptor tyrosine kinase | Homo sapiens |
4 | We detected sustained overexpression of Axl in CLL B-cells from CLL patients on ibrutinib treatment, suggests targeting Axl could be a promising strategy to overcome drug resistance and killing of CLL B-cells in these patients. | ibrutinib | AXL receptor tyrosine kinase | Homo sapiens |