PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30647852-0 2018 Chronic lymphocytic leukemia cells from ibrutinib treated patients are sensitive to Axl receptor tyrosine kinase inhibitor therapy. ibrutinib 40-49 AXL receptor tyrosine kinase Homo sapiens 84-87 30647852-3 2018 Ibrutinib-exposed CLL B-cells were treated with increasing doses (0.01- 0.50muM) of a new formulation of high-affinity Axl inhibitor, TP-0903 (tartrate salt), for 24 hours and LD50 doses were determined. ibrutinib 0-9 AXL receptor tyrosine kinase Homo sapiens 119-122 30647852-5 2018 We detected sustained overexpression of Axl in CLL B-cells from CLL patients on ibrutinib treatment, suggests targeting Axl could be a promising strategy to overcome drug resistance and killing of CLL B-cells in these patients. ibrutinib 80-89 AXL receptor tyrosine kinase Homo sapiens 40-43 30647852-5 2018 We detected sustained overexpression of Axl in CLL B-cells from CLL patients on ibrutinib treatment, suggests targeting Axl could be a promising strategy to overcome drug resistance and killing of CLL B-cells in these patients. ibrutinib 80-89 AXL receptor tyrosine kinase Homo sapiens 120-123